crippling

深刻な借金

Refers to a level of debt so large that it is impossible or nearly impossible for the borrower to repay, causing severe financial hardship.

深刻な影響

Indicates a consequence or result that severely damages or weakens a system, organization, or person.

身体を不自由にする怪我

A physical injury that is so severe it causes permanent disability or severely impairs movement or function.

永久的な損傷と運動能力の喪失を引き起こす怪我を説明する

Describes a responsibility, duty, or debt that is extremely difficult to manage and severely limits one's freedom or progress.

深刻な打撃を与えるストライキ

A work stoppage by employees that causes severe disruption to an industry, company, or public service.

Refers to an event or action that causes severe damage or harm to someone's hopes, plans, or confidence.

重度の脳卒中

A stroke (sudden interruption of blood supply to the brain) that results in severe and permanent loss of function, such as paralysis.

麻痺などの重篤で永続的な機能喪失をもたらす脳卒中（脳への血液供給の突然の中断）。

壊滅的な禁輸措置

An official ban on trade or other commercial activity with a particular country that causes severe economic harm to it.

対象国の経済に深刻な損害を与える禁輸措置。